Medical Genetics: TeratogensWhat is a teratogen?A teratogen (ter-AT-uh-jen) is something that can cause or raise the risk for a birth defect in a baby. They are things that a mother may be exposed to during her pregnancy. Teratogens include: Show
The riskiest times of pregnancyExperts believe that teratogens can begin affecting a baby growing in the womb about 10 to14 days after conception. Conception is when a woman’s egg is fertilized by a man’s sperm. After conception, it takes about 6 to 9 days for the egg to implant in the uterus. Once the fertilized egg is attached to the uterus, the mother and the embryo share a blood supply. Chemicals in the mother's blood can then affect the growing baby. As a baby grows in the womb, teratogens may affect parts of the baby’s body as they are forming. For example, the neural tube closes in the first 3 to 5 weeks of the pregnancy. During this time, teratogens can cause neural tube defects such as spina bifida. Some organs are sensitive to teratogens during the whole pregnancy. This includes the baby's brain and spinal cord. Alcohol affects the brain and spinal cord, so it can cause harm at any time during pregnancy. This is why you should not drink alcohol if you are pregnant. How are teratogens known?Researchers have two ways of finding out if a substance is a teratogen. They are:
What are nonteratogenic agents?Certain things have been shown to not cause birth defects. These are called nonteratogenic agents. These include:
Talking with your healthcare providerIf you’re pregnant, talk with your healthcare provider about things to avoid during pregnancy that may cause birth defects. He or she can help answer your questions and help you have a safe pregnancy. What is a teratogen?A teratogen is an agent, which can cause a birth defect. It is usually something in the environment that the mother may be exposed to during her pregnancy. It could be a prescribed medication, a street drug, alcohol use, or a disease present in the mother which could increase the chance for the baby to be born with a birth defect. About 4 to 5 percent of birth defects are caused by exposure to a teratogen. What are the most sensitive periods for teratogens in pregnancy?Once the egg is fertilized (conception), it takes about six to nine days for implantation (anchoring into the uterus) to occur. Once the fertilized egg is connected to the uterus, a common blood supply exists between the mother and the embryo. In other words, if something is in the mother's blood, it can now cross over to the developing fetus. Teratogens are thought to have the ability to effect the fetus about 10 to14 days after conception. During the development of a baby, there are certain organs forming at certain times. If a teratogen has the potential to interfere with the closure of the neural tube, for example, the exposure to the teratogen must occur in the first 3.5 to 4.5 weeks of the pregnancy, since this is when the neural tube is closing. There are some organ systems that are sensitive to teratogens throughout the entire pregnancy, such as the central nervous system. The central nervous system is the baby's brain and spine. One teratogen that affects the central nervous system is alcohol. Alcohol, at any time during the pregnancy, has the potential to cause birth defects and health problems in the baby, since the central nervous system is sensitive to teratogens the entire nine months of gestation. This is why alcohol consumption should be avoided in its entirety during pregnancy. There are many different teratogens that cause birth defects. Listed in the directory below are some, for which we have provided a brief overview.
What are the three most common teratogens?Common teratogens include some medications, recreational drugs, tobacco products, chemicals, alcohol, certain infections, and in some cases, uncontrolled health problems in the birthing parent. Alcohol is a well-known teratogen that can cause harmful effects on the fetus after exposure at any time during pregnancy.
What are 5 types of teratogens?Known Teratogens. angiotensin converting enzyme (ACE) inhibitors, such as Zestril and Prinivil.. alcohol.. aminopterin.. androgens, such as methyltestosterone (Android). busulfan (Myleran). carbamazepine (Tegretol). chlorobiphenyls.. cocaine.. What are teratogens give examples?A teratogen is a substance that may lead to birth defects in an embryo or fetus. During pregnancy, exposure to certain chemicals, infections, and drugs may increase the risk that a person will miscarry or that the embryo or fetus could have a developmental abnormality. Alcohol and smoking are two common teratogens.
What is one of the most commonly used teratogens?One of the most commonly used teratogens is alcohol and because half of all pregnancies in the United States are unplanned, it is recommended that women of child-bearing age take great caution against drinking alcohol when not using birth control or when pregnant (Surgeon General's Advisory on Alcohol Use During ...
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