When you think about fat, you might picture it as your body’s insulation layer or storage for extra calories. But fat plays a much bigger role in the body. And if you assume that all fat is unhealthy, it's time to update your thinking. Fat is found throughout the body: inside your nerves and bones, around your heart and blood vessels,
and even behind your eyeballs. We need it to function and survive. “Think of fat as a mastermind in our bodies,” says Silvia Corvera, MD, a professor at the UMass Chan Medical School. “When things affect fat, it affects our entire body.” Body fat, or adipose tissue, is a complex organ. It contains fat cells, nerves, immune cells, and connective tissue. Its main job is to store and release energy, depending on the
body’s needs, says Susan K. Fried, PhD, a professor at the Icahn School of Medicine at Mount Sinai. Fat responds to signals like the hormone insulin, which tells adipose tissue to store fat. “There are also nerves that go from your brain to your fat and say, ‘Hey, we don’t have enough energy here. Can you liberate some fat because other cells in the body need it?’ ” Fried says. Fat tissue is also a major maker of hormones, chemical messengers that communicate with tissues and organs throughout the body. “It’s a classic endocrine organ, the biggest one in the body,” Fried says. Hormones produced by adipose tissue regulate metabolism and insulin sensitivity. They help the body use nutrients efficiently. For example,
it’s the primary producer of adiponectin. This hormone increases insulin sensitivity – a good thing for keeping blood glucose levels in check – and decreases inflammation. Too little adiponectin can lead to type 2 diabetes and other metabolic diseases. Another hormone is leptin, which controls appetite. “If you have no adipocytes [fat cells], you have no leptin. You feel like you
have no energy stores and get ravenously hungry,” Corvera says. Fat tissue also releases other substances that influence inflammation and immune function.The Function of Fat
While all fat cells might look alike from the outside, they can have different functions, depending on their type. There are three main types of fat cells. Researchers are studying whether they can harness the positive traits of brown and beige fat and use them to treat obesity. Fat also behaves differently depending on where it’s located: the belly, thigh, or near your organs. When it comes to health, location matters.Different Types of Fat Cells
Location
Matters
Fat is an essential part of our bodies. Too little or too much fat is unhealthy. “You have to have the right amount,” says Fried, but the right amount varies from person to person. An important consideration is how much tissue you have available to store fat, which can depend on your genes. “If you don’t have the capacity to make a lot of fat, you won’t have enough
space to store extra calories,” Corvera says. “It will spill over into your liver, muscles, and heart. That’s what gives rise to metabolic disease.” Rather than thinking about weight or percentage of body fat, consider your waist-to-hip ratio. Research suggests
that the way fat is distributed across the body matters more than the amount of body fat when it comes to overall health. To get your waist-to-hip ratio, use a tape measure to measure your waist and hips in centimeters. Divide your waist measurement by your hip measurement. The World Health Organization says that the risk of health issues is greater for men who have a waist-to-hip ratio of 0.90 or higher, and for women with a waist-to-hip ratio of 0.85 centimeters or higher. You can also just check your waist circumference. The chances of health problems related to obesity are higher for men with a waist of more than 40 inches, and for a woman (who’s not pregnant) with a waist circumference of more than 35 inches, according to the CDC. “People realized that waist size is a risk factor for type 2 diabetes, other chronic disease, and even premature death,” Fried says. Conversely, having more body fat in your lower body may help protect your health.How Much Is Too Much?
Research also suggests that fat behaves differently in women and men. In one study, higher muscle mass seemed to protect women and men from cardiovascular disease. But women with higher fat, regardless of muscle mass, were less likely to die of heart disease – but only if their blood pressure, blood sugar, and cholesterol were under control. (Whether they were taking hormone replacement therapy for menopausal symptoms also mattered.).
Body fat isn’t just about your size or how you look. “What matters is how it affects your health,” Corvera says. “You have to have healthy adipose tissue to be healthy in all other aspects of your physical and mental health.”