What is the causative agent of elk wasting disease?

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Table of Contents Show

Disease Background
Geographic Range
Transmission
Wildlife Health Implications
Species Affected
Clinic Signs
Course of Disease
Public Health Implications
Guidance to Park Visitors
What is wasting disease in elk?
What is the cause of wasting disease?
Is elk Chronic wasting disease caused by prions?
What bacteria causes chronic wasting disease?

NPS Photo/ M. Reed

Disease Background

Chronic wasting disease (CWD) is a prion disease which is a unique family of diseases caused by a malformed protein.
CWD infects animals in the cervid family (deer, elk, moose, and reindeer).
The malformed prion protein accumulates in the brain and other tissues causing neurological signs, emaciation, and death. Once clinical signs are observed the disease is always fatal.

Geographic Range

CWD was initially identified in Colorado and Wyoming in the 1960s and 1970s but has since spread east across the United States and west as far as Utah.
It has been detected in free-ranging or captive cervids in at least 24 U.S. states, two Canadian provinces, South Korea, and in European reindeer and moose.
Translocation of wild, captive, and privately-owned deer and elk is an important contributing factor in human-mediated spread of CWD across the country and globe to new regions. Natural migration has also contributed to disease spread.

Transmission

Abnormal prions are shed in saliva, urine, feces, blood, and antler velvet from infected hosts (clinical or subclinical). The carcass of an animal that has died of CWD is also highly contaminated with infectious prion.
Transmission occurs by direct contact with live infected animals or indirectly through contact with contaminated environments.
Prions are extremely resistant to heat, ultraviolet radiation, and disinfectants allowing them to persist in the environment for very long periods of time (years to decades).

Wildlife Health Implications

Species Affected

In North America, white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), elk (Cervus canadensis), and moose (Alces alces) have been documented with natural infection.
Reindeer (Rangifer tarandus) in Norway

Clinic Signs

Infected cervids lose weight and body condition, resulting in emaciation and death.
Neurologic signs and behavior changes include depression, altered gait, head tremors, teeth grinding, hypersalivation, difficulty swallowing, circling, lowering of the head, drooping of the ears, and isolation from other animals

Course of Disease

Depending on the host species, the incubation and pre-clinical period may be as short as 12 months but is often much longer (2+ years).
During this time the animal can be shedding infectious prions. Since it is difficult to diagnose disease during incubation, management options are limited.
Diagnosis requires collection of brainstem, lymph nodes, or rectal tissue for diagnostic tests run in a laboratory.

Prevention

There is no vaccine or treatment for CWD.
The most important wildlife management tool to prevent the spread of CWD is limiting human assisted cervid movement across the landscape and preventing artificial congregation of cervids in infected or potentially infected environments (feeding grounds, bait stations).

Public Health Implications

There is currently no evidence that CWD can infect humans or domestic animal species. However, it is recommended that tissues from CWD infected animals not be consumed.

Guidance to Park Visitors

The guidelines below can be followed to ensure you and your family safely enjoy the wonderful natural and cultural resources protected by the NPS.

Notify a Park Service employee as soon as possible and avoid contact with the animal if you see any sick or dead wildlife.

Most wild animals in parks are healthy and thrive in their natural environment, but sometimes wildlife can get sick just like people.
Some disease-causing organisms can be passed between wild animals and people. Therefore, always avoid touching or handling sick or dead wild animals.
Park Service employees trained in wildlife health use specific protective measures to safely deal with a wild animal that may have died of disease.

It is recommended that people avoid consumption of any part of an animal that is suspected or confirmed to have CWD.

What is wasting disease in elk?

What is chronic wasting disease? CWD is a disease found in some deer, elk and moose populations. CWD damages portions of the brain and typically causes progressive loss of body condition, behavioral changes, excessive salivation and death.

What is the cause of wasting disease?

Chronic wasting disease is caused by a misfolded protein called a prion. All mammals produce normal prions that are used by cells, then degraded and eliminated, or recycled, within the body. When disease-associated prions contact normal prions, they cause them to refold into their own abnormal shape.

Is elk Chronic wasting disease caused by prions?

Chronic wasting disease (CWD) is a prion disease that affects deer, elk, reindeer, sika deer and moose. It has been found in some areas of North America, including Canada and the United States, Norway and South Korea.

What bacteria causes chronic wasting disease?

The most prominent is Dr. Frank Bastian, a pathologist at Louisiana State University. He argues that a unique super-bacteria known as spiroplasma causes transmissible spongiform encephalopathies such as CWD.