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The correct answer is option a. A hydrogen bond is formed when the H atom gets covalently bonded to more electronegative atoms like N, F, and O. Individually, hydrogen bonds are very weak and can be easily broken. Hence option (a) is the correct choice. A strong hydrogen bonding is found in water, where the H atom of one of the water molecules interacts with the lone pair of electrons on the oxygen atom of the other water molecule. Hence option (b) is the incorrect choice. In the beta-sheet structure, the polypeptide chains are held together by hydrogen bonds. These hydrogen bonds are responsible for the stability of the beta-sheets and thereby this option can be neglected. Hydrogen bonds are responsible for the high stability of double-stranded DNA. Between the two strands, hydrogen bonds are formed by the complementary pairing of a base from one strand with a base from the other. Hence this statement is true and hence the option can be neglected. In alpha-helix, hydrogen bonds are formed between -CO and -NH groups of the main chain. These hydrogen bonds are responsible for the high stability of the alpha-helix. Hence this option is also neglected.
a) One characteristic of water is that it has a high boiling point which is 100 degrees Celsius. This high boiling point is due to the existence of H-bonds (hydrogen bonds) which require a high amount of energy for their breakage. Hence, the incorrect option is (a). b) Potentially water (H2O) has the ability to form 4 H-bonds with other neighboring water molecules. Two H-bonds can be formed with the 2 H (hydrogen) atoms and two H-bonds can be formed with one oxygen molecule (contains 2 lone pairs of electrons). Hence, the incorrect option is (b). c) The covalent bonds are much stronger than individual H-bonds because in covalent bonding there is actual sharing of electrons while in H-bonding there is an attraction (due to electronegativity difference) between the atoms. Hence, the incorrect option is (c). d) Individual H-bonds cannot exist in water as H-bond formation requires the existence of at least two water molecules. Hence, the correct option is (d). e) The strength of the H-bonds depends on several factors like temperature, linearity, bond angle, environment, and more. Hence, the incorrect option is (e). Recommended textbook solutions
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Organizational Behavior: Managing People and Organizations13th EditionJean Phillips, Ricky W. Griffin, Stanley Gully 174 solutions letter start the question the question says that which of the following statement is not true first option is intramolecular hydrogen bonds are formed between two different molecules of compound this statement is correct inter means between two molecules second option intramolecular hydrogen bonds are formed between two different molecules of same compound this is wrong because it remains same molecule intramolecular hydrogen bonding should be between three molecule not between different compounds it must be in same compound so answer is correct now being strong let's see the sea option intramolecular hydrogen bonds are formed within molecules this is correct in term of hydrogen bonds are have strong influence on physical properties of compound this is true this is correct physical properties mants boiling point and melting point so this is also correct we have to choose which is not true so we will be the right answer thank you Answer the following questions and then press 'Submit' to get your score. Question 1Which of the following statements best describes structure-activity relationships (SAR)? a) The study of which functional groups are important to the chemical reactivity of the drug. b) The study of the physicochemical properties that are important to the absorption of a drug into the blood supply. c) The study of the structural features of a drug that are important to its biological activity. d) The study of the structural features of a drug that are important to its chemical stability. Question 2Which of the intermolecular bonding interactions below are possible for an alcohol? a) Hydrogen bonding only b) van der Waals interactions only c) Ionic bonding only d) Both hydrogen bonding and ionic bonding Question 3Which of the intermolecular bonding interactions below are possible for a primary amine? a) Hydrogen bonding only b) van der Waals interactions only c) Ionic bonding only d) Both hydrogen bonding and ionic bonding Question 4Which of the intermolecular bonding interactions below are possible for an alkene? a) Hydrogen bonding only b) Van der Waals interactions only c) Ionic bonding only d) Both hydrogen bonding and ionic bonding Question 5Which of the intermolecular bonding interactions below are possible for a secondary amide? a) Hydrogen bonding only b) van der Waals interactions only c) Ionic bonding only d) Both hydrogen bonding and ionic bonding Question 6Which of the intermolecular bonding interactions below are possible for a ketone? a) Hydrogen bonding only b) van der Waals interactions only c) Ionic bonding only d) Both hydrogen bonding and ionic bonding Question 7Which of the following statements is true regarding an ether? a) It can only participate in hydrogen bonding as a hydrogen bond donor. b) It can only participate in hydrogen bonding as a hydrogen bond acceptor. c) It can participate in hydrogen bonding both as a hydrogen bond donor and a hydrogen bond acceptor. d) It cannot participate in hydrogen bonding at all. Question 8Which of the following statements is true regarding an alkene? a) It can only participate in hydrogen bonding as a hydrogen bond donor. b) It can only participate in hydrogen bonding as a hydrogen bond acceptor. c) It can participate in hydrogen bonding both as a hydrogen bond donor and a hydrogen bond acceptor. d) It cannot participate in hydrogen bonding at all. Question 9Which of the following statements is true regarding a secondary amide? a) It can only participate in hydrogen bonding as a hydrogen bond donor. b) It can only participate in hydrogen bonding as a hydrogen bond acceptor. c) It can participate in hydrogen bonding both as a hydrogen bond donor and a hydrogen bond acceptor. d) It cannot participate in hydrogen bonding at all. Question 10Which of the following major aims in drug design is not related to the pharmacodynamics of a drug? a) The reduction of side effects b) The maximisation of activity c) The reduction of toxicity d) The maximisation of oral bioavailability Question 11N-Phenethylmorphine
was synthesised from morphine and found to have enhanced activity. What drug design strategy was used here? a) Simplification b) Extension c) Rigidification d) Conformational blocker Question 12SAR shows that the important binding groups in morphine are the phenol, aromatic ring and amine. A diagram can be drawn which shows these functional groups and their relative orientations. What is the term for this? a) Pharmacodynamics b) Pharmacokinetics c) Chromophore d) Pharmacophore Question 13It is common practice to vary the length and size of alkyl groups when making analogues of a lead compound. Which of the following statements is not true? a) Replacing a straight chain alkyl group with a branched alkyl group may increase activity by filling up a hydrophobic pocket and increasing van der Waals interactions. b) Increasing the chain length or size of an alkyl group may increase target selectivity if one target binding site is more spacious than another. c) Increasing the chain length or size of an alkyl group increases activity and selectivity by stabilising the analogue. d) Increasing the chain length of an alkyl group may increase activity by leading to better van der Waals interactions with a hydrophobic region of the binding site. Question 14Which of the following is not true of analogues produced by a rigidification strategy? a) They have a smaller number of conformations. b) They are easier to synthesise. c) They are likely to be more selective. d) They are likely to be more active. Question 15Structure (I) has a highly flexible side chain. Which of the following statements is true? a) A flexible molecule is more likely to be in its active conformation when it approaches its target binding site. This results in increased activity. b) A flexible molecule is more likely to adopt conformations that will bind to different targets, resulting in side effects. c) A flexible molecule may be able to bind to its target binding site in different binding modes, resulting in an increase in activity. d) A flexible molecule is more likely to show target selectivity. Which statement is not true about hydrogen bonds?Answer and Explanation: The answer is D). Hydrogen bonding does not form in salts such as NaCl.
Which of the following statements are true about hydrogen bonds?The correct answer: The true statement about the hydrogen bond is c. Hydrogen bond is weak force between atoms in a molecule but is of enormous importance in physiology.
What must be true for hydrogen bonds?In order for a hydrogen bond to occur there must be both a hydrogen donor and an acceptor present. The donor in a hydrogen bond is usually a strongly electronegative atom such as N, O, or F that is covalently bonded to a hydrogen bond.
Which of the following is true for hydrogen?Hydrogen is combustible and non-supporter of combustion and this could be understood by a small activity in which if burning candle is placed in a hydrogen gas-filled gas jar with its mouth downwards then light candle gets extinguished but the gas burns with a pop-up sound.
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Which of the following statements is not true about hydrogen bond?
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