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This is an NCLEX review for iron-deficiency anemia. Patients who have iron-deficiency anemia are suffering from low red blood cells and/or hemoglobin levels. This leads to the patient experiencing low levels of oxyen throughout the body. In the previous review, I covered other hematology disorders. So, if you are studying for NCLEX or your nursing lecture exams be sure to check out that section. When taking care of a patient with iron-deficiency anemia it is very important the nurse knows how to recognize the typical signs and symptoms seen in this condition, how it is diagnosed, nursing interventions, and patient education. Don’t forget to take the iron-deficiency anemia quiz. In this NCLEX review for iron-deficiency anemia, you will learn the following: Definition of iron-deficiency anemia Pathophysiology of iron-deficiency anemia Causes Treatment Signs and Symptoms Nursing Interventions Lecture on Iron-Deficiency AnemiaIron-Deficiency Review NotesDefinition: a type of anemia that is caused by low IRON levels. What is Anemia? Anemia is a decreased amount of red blood cells or hemoglobin in the body. These components play a huge role in carrying oxygen throughout the body. If you are low in RBCs or hemoglobin, your body won’t receive enough oxygen to function properly. Key Points about Iron-Deficiency Anemia:
Pathophysiology of Iron Deficiency AnemiaThe red blood cells transport oxygen throughout the body and remove carbon dioxide (a waste product from metabolism) with the help of hemoglobin. Hemoglobin is an “ingredient” found in the RBC that is a protein that contains IRON.
Remember low IRON levels: mean less production of hemoglobin which means less oxygen to the body. Causes of Iron-Deficiency Anemia
Signs and Symptoms of Iron-Deficiency AnemiaRemember the Mnemonic: “Low Iron” Lethargic Overexerted easily (may be short of breath) Weird food cravings (ice, dirt, clay), White-faced (pale) Inflammation of tongue…will become smooth and turn various colors of red (due to lack of oxygen it receives), Increased Heart rate (trying to compensate for the low oxygen) Reduced Hemoglobin level Observe changes in RBCs with a blood smear test…will appear hypochromic (pale) and microcytic (small) Nail changes (Koilonychias….spoon-shaped nails), neuro change (confused, moody) Diagnosed?
Nursing Interventions for Iron-Deficiency Anemia
Egg yolks Apricots Tofu Legumes, Leafy green vegetables Oysters Tuna Sardines, Seeds pOtatoes Fish (halibut, haddock, salmon) Iron-fortified cereal and breads Raisins, Red meats (beef) pOultry (turkey, chicken) Nuts More NCLEX Reviews References
Learning Outcome
The word anemia derives from an ancient Greek word anaimia, meaning “lack of blood.” Anemia, like a fever, is not a diagnosis but a presentation of an underlying disease. Multiple diseases can present as anemia due to various mechanisms. Anemia affects a significant number of people worldwide (more so in the developing world), resulting in a considerable increase in the cost of medical care. Anemia can be defined as a reduction in hemoglobin (less than 13.5 g/dL in men; less than 12.0 g/dL in women) or hematocrit (less than 41.0% in men; less than 36.0% in women) or red blood cell (RBC) count. The terms hemoglobin and hematocrit are more commonly used than RBC count in day-to-day clinical practice. There are different lower limits of normal range based on ethnicity, gender, and age. Anemia causes decreased oxygen-carrying capacity of the blood leading to tissue hypoxia. Grading of Anemia, according to the National Cancer Institute, is as follows:
Anemia classified into acute anemia and chronic anemia. Acute anemia is predominantly due to acute blood loss or acute hemolysis. Chronic anemia is more common and is secondary to multiple causes. Nursing DiagnosisEtiology of chronic anemia based on mean corpuscular volume (MCV is the average size of RBC). Microcytic Anemia (MCV less than 80 femtoliters [fL])
Macrocytic Anemia (MCV greater than 100 fL)
Normocytic Anemia (MCV 80 to 100 fL)
Some conditions can present in more than 1 classification. For example, early iron deficiency can be normocytic. Anemia of chronic disease is mostly normocytic but can be microcytic too. Hemolytic anemia[2] can cause either macrocytic or normocytic anemia. Iron deficiency anemia is the most common type of anemia, affecting approximately 8% to 9% of the world’s population. Anemia is more prevalent in:
Symptoms and signs of chronic anemia are mostly due to decreased tissue oxygenation from the reduction of the oxygen-carrying capacity of the blood. Symptoms are worse when anemia is severe, with a rapid decrease in hemoglobin/HCT and with increased oxygen demands states like exercise. Common presenting symptoms include:
A detailed history should include medical history, home medications, alcohol use, and family history. Ethnicity and country of origin are also helpful. Important examination findings include:
Initial Work-Up
Differentiation of Microcytic Anemias Based on Iron Studies
Peripheral smear, hemoglobin electrophoresis, and bone marrow examination if needed. Further testing would include esophagogastroduodenoscopy (EGD) and colonoscopy if gastrointestinal (GI) bleeding is suspected and imaging studies if malignancy suspected. Chronic anemia is managed predominantly in outpatient settings. They need hospitalization if:
If hemoglobin is less than 7 g/dL or if a patent is symptomatic, transfusion of packed red blood cells (PRBC) is indicated. Transfusions should be done with caution in patients with volume overload status like end-stage renal disease (on hemodialysis) and congestive heart failure (CHF). Other treatments include treating underlying conditions as below.
Nursing Management
When To Seek Help
Outcome Identification
Monitoring
Chronic anemia is a very common condition seen in day-to-day clinical practice and managed in outpatient settings. Anemia management can range from simple to complex based on the underlying condition causing it. Most of the time patient's primary care physician needs help with a specialist based on underlying condition either a gastroenterologist or a hematologist or a nephrologist or a gynecologist. It is very important to have good interprofessional communication and care coordination for the management of anemia appropriately and promptly. This would help both in correcting anemia and treating underlying conditions. Anemia is a condition with decreased oxygen-carrying capacity of the blood. Anemia is very common and caused by different conditions ranging from simple nutritional deficiencies (iron, vitamin B12, and folic acid) to blood loss to other complicated causes. Anemia is a common medical condition and easily diagnosed with a simple blood work CBC. Treatment can be simple like nutritional supplements (iron, vitamin B12, and folic acid) to blood transfusion to treating complex underlying conditions. It is very important to follow up with the doctor and sometimes with a specialist to treat anemia because untreated anemia can be life-threatening and may even cause death. Discharge Planning
Pearls and Other issues
Review Questions1. Tas F, Eralp Y, Basaran M, Sakar B, Alici S, Argon A, Bulutlar G, Camlica H, Aydiner A, Topuz E. Anemia in oncology practice: relation to diseases and their therapies. Am J Clin Oncol. 2002 Aug;25(4):371-9. [PubMed: 12151968] 2.Sachdev V, Rosing DR, Thein SL. Cardiovascular complications of sickle cell disease. Trends Cardiovasc Med. 2021 Apr;31(3):187-193. [PMC free article: PMC7417280] [PubMed: 32139143] 3.Baradwan S, Alyousef A, Turkistani A. Associations between iron deficiency anemia and clinical features among pregnant women: a prospective cohort study. J Blood Med. 2018;9:163-169. [PMC free article: PMC6174908] [PubMed: 30323700] 4.Lanier JB, Park JJ, Callahan RC. Anemia in Older Adults. Am Fam Physician. 2018 Oct 01;98(7):437-442. [PubMed: 30252420] 5.Kunireddy N, Jacob R, Khan SA, Yadagiri B, Sai Baba KSS, Rajendra Vara Prasad I, Mohan IK. Hepcidin and Ferritin: Important Mediators in Inflammation Associated Anemia in Systemic Lupus Erythematosus Patients. Indian J Clin Biochem. 2018 Oct;33(4):406-413. [PMC free article: PMC6170241] [PubMed: 30319186] 6.Anand S, Thomas B, Remuzzi G, Riella M, Nahas ME, Naicker S, Dirks J. Kidney Disease. In: Prabhakaran D, Anand S, Gaziano TA, Mbanya JC, Wu Y, Nugent R, editors. Cardiovascular, Respiratory, and Related Disorders. 3rd ed. The International Bank for Reconstruction and Development / The World Bank; Washington (DC): Nov 17, 2017. [PubMed: 30212067] 7.Hong CT, Hsieh YC, Liu HY, Chiou HY, Chien LN. Association Between Anemia and Dementia: A Nationwide, Populationbased Cohort Study in Taiwan. Curr Alzheimer Res. 2020;17(2):196-204. [PubMed: 32183675] 8.Agbozo F, Abubakari A, Der J, Jahn A. Maternal Dietary Intakes, Red Blood Cell Indices and Risk for Anemia in the First, Second and Third Trimesters of Pregnancy and at Predelivery. Nutrients. 2020 Mar 15;12(3) [PMC free article: PMC7146471] [PubMed: 32183478] 9.Ray JG, Davidson A, Berger H, Dayan N, Park AL. Haemoglobin levels in early pregnancy and severe maternal morbidity: population-based cohort study. BJOG. 2020 Aug;127(9):1154-1164. [PubMed: 32175668] |