In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For adapalene, the following should be considered: Show
AllergiesTell your doctor if you have ever had any unusual or allergic reaction to adapalene or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. PediatricStudies of adapalene have been done only in adult patients, and there is no specific information comparing use of adapalene in children up to 12 years of age with use in other age groups. In teenagers, adapalene is not expected to cause different side effects or problems than it does in adults. GeriatricMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of adapalene in the elderly with use in other age groups. Older adults are not likely to develop acne. BreastfeedingThere are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Interactions with medicinesAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine. Interactions with food/tobacco/alcoholCertain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other medical problemsThe presence of other medical problems may affect the use of adapalene. Make sure you tell your doctor if you have any other medical problems, especially:
Proper use of adapaleneIt is very important that you use adapalene only as directed. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause irritation of the skin. Do not apply adapalene to windburned or sunburned skin or on open wounds. Do not use adapalene in or around the eyes, lips, or inside of the nose. Spread the medicine away from these areas when applying. If the medicine accidently gets on these areas, wash with water at once. Apply the medicine to clean, dry areas of the skin affected by acne. Rub in gently and well. Wash your hands afterwards to remove any medicine that may remain on them. To help clear up your acne completely, it is very important that you keep using adapalene for the full time of treatment , even if your symptoms begin to clear up after a short time. If you stop using adapalene too soon, your acne may return or get worse. DosingThe dose of adapalene will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of adapalene. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Missed doseIf you miss a dose of adapalene, skip the missed dose and go back to your regular dosing schedule. Do not double doses. StorageStore the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Precautions while using adapaleneDuring the first 3 weeks you are using adapalene, your acne may seem to get worse before it gets better. Full improvement should be seen within 12 weeks, especially if you use the medicine every day. You should not stop using adapalene if your acne seems worse at first, unless irritation or other symptoms become severe. Check with your doctor if your acne does not improve within 8 to 12 weeks. Do not apply any topical product to the same area where you are using adapalene, unless otherwise directed by your doctor. If applied to the same area treated with adapalene, the following products may cause mild to severe irritation of the skin:
Your doctor may ask you to use other topical products, such as benzoyl peroxide, clindamycin, or erythromycin, during your treatment with adapalene. Applying the products at different times of the day will lessen the chance of causing skin irritation. If your skin becomes too dry or red at any time, discuss with your doctor whether you should continue using adapalene. Applying creams, lotions, or moisturizers as needed helps lessen these skin problems. During treatment with adapalene, avoid getting too much sun on treated areas and do not use sunlamps. Since your skin may be more prone to sunburn or skin irritation, use sunscreen or sunblocking lotions regularly with a sun protection factor (SPF) of 15 or more. Wear protective clothing against sun, wind, and cold weather. Adapalene side effectsAlong with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor as soon as possible if any of the following side effects occur: More common - especially during the first month of use
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Rare - more common during the first month of useOther side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088. Frequently asked questionsMore about adapalene topicalPatient resourcesOther brandsDifferin Professional resourcesRelated treatment guidesFurther informationAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Is it OK to use adapalene longConclusion: In consistence with previous clinical findings, the use of adapalene-BPO in daily practice routine is safe and effective in the long-term management of patients with moderate to severe acne.
How long does adapalene take to remove scars?Adapalene/benzoyl peroxide gel reduces atrophic acne scars, lesions up to 48 weeks.
Should adapalene be used daily?Can Adapalene be used daily? Yes, one must use it regularly for 4-8 weeks, once daily at bedtime, for best results. It's better to apply it in the nighttime for at least 1-2 hours, as there will be no sun exposure at that time.
Can too much adapalene cause acne?Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using the medication. These effects usually decrease with continued use. If any of these effects lasts or gets worse, tell your doctor or pharmacist promptly.
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