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Heritability (weighted means and ranges) of 10 addictive disorders: hallucinogens, cannabis, stimulants, sedatives, opiates, and cocaine dependence or abuse; alcohol dependence; smoking; caffeine consumption or heavy use; pathologic gambling. Weighted heritability (h2) means were computed using data from large surveys of adult twins. (Adapted from Goldman D, Oroszi G, Ducci F. The genetics of addictions: uncovering the genes. Nat Rev Genet 2005;6(7):521–32.)